Ontology highlight
ABSTRACT:
SUBMITTER: Ji HJ
PROVIDER: S-EPMC7795626 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Ji Hong-Jian HJ Li Jia-Yuan JY Wu Shi-Fei SF Wu Wen-Yong WY Yao Chang-Liang CL Yao Shuai S Zhang Jian-Qing JQ Guo De-An DA
Molecules (Basel, Switzerland) 20201223 1
Twelve compounds, including two new aristolochic acid analogues with a formyloxy moiety (9-10) and 10 known aristolochic acid derivates (1-8 and 11-12), were obtained from the roots of <i>Aristolochia</i><i>contorta</i>. Their structures were elucidated using extensive spectroscopic methods. Their cytotoxic activity in human proximal tubular cells HK-2 was evaluated by the MTT method, which has been widely used to assess cell viability. Among these molecules, compounds <b>3</b> and <b>9</b> were ...[more]