Unknown

Dataset Information

0

Oxygen Saturation Imaging Using LED-Based Photoacoustic System.


ABSTRACT: Oxygen saturation imaging has potential in several preclinical and clinical applications. Dual-wavelength LED array-based photoacoustic oxygen saturation imaging can be an affordable solution in this case. For the translation of this technology, there is a need to improve its accuracy and validate it against ground truth methods. We propose a fluence compensated oxygen saturation imaging method, utilizing structural information from the ultrasound image, and prior knowledge of the optical properties of the tissue with a Monte-Carlo based light propagation model for the dual-wavelength LED array configuration. We then validate the proposed method with oximeter measurements in tissue-mimicking phantoms. Further, we demonstrate in vivo imaging on small animal and a human subject. We conclude that the proposed oxygen saturation imaging can be used to image tissue at a depth of 6-8 mm in both preclinical and clinical applications.

SUBMITTER: Bulsink R 

PROVIDER: S-EPMC7795655 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC6684596 | biostudies-literature
| S-EPMC5723278 | biostudies-literature
| S-EPMC7443711 | biostudies-literature
| S-EPMC6761607 | biostudies-literature
| S-EPMC7671861 | biostudies-literature
| S-EPMC4605073 | biostudies-other
| S-EPMC7203680 | biostudies-literature
| S-EPMC5844348 | biostudies-literature
| S-EPMC4158672 | biostudies-literature
| S-EPMC6384193 | biostudies-literature