Ontology highlight
ABSTRACT:
SUBMITTER: Sobat M
PROVIDER: S-EPMC7797908 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Sobat Motahareh M Asad Sedigheh S Kabiri Mahboubeh M Mehrshad Maliheh M
iScience 20210105 1
By screening 27,000 publicly available prokaryotic genomes, we recovered ca. 6300 type I and ca. 5200 type II putative L-asparaginase highlighting the vast potential of prokaryotes. Caspian water with similar salt composition to the human serum was targeted for <i>in silico</i> L-asparaginase screening. We screened ca. three million predicted genes of its assembled metagenomes that resulted in annotation of 87 putative L-asparaginase genes. The L-asparagine hydrolysis was experimentally confirme ...[more]