Ontology highlight
ABSTRACT:
SUBMITTER: Pinto G
PROVIDER: S-EPMC7800365 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Pinto Giulia G Saenz-de-Santa-Maria Inés I Chastagner Patricia P Perthame Emeline E Delmas Caroline C Toulas Christine C Moyal-Jonathan-Cohen Elizabeth E Brou Christel C Zurzolo Chiara C
The Biochemical journal 20210101 1
Glioblastoma (GBM) is the most aggressive brain cancer and its relapse after surgery, chemo and radiotherapy appears to be led by GBM stem cells (GSCs). Also, tumor networking and intercellular communication play a major role in driving GBM therapy-resistance. Tunneling Nanotubes (TNTs), thin membranous open-ended channels connecting distant cells, have been observed in several types of cancer, where they emerge to drive a more malignant phenotype. Here, we investigated whether GBM cells are cap ...[more]