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Molecular basis for protein-protein interactions.


ABSTRACT: This minireview provides an overview on the current knowledge of protein-protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein-protein interactions and their molecular interactions is important for a number of applications, including drug design. Protein-protein interactions and their discovery are thus an interesting avenue for understanding how protein complexes, which make up the majority of proteins, work.

SUBMITTER: Seychell BC 

PROVIDER: S-EPMC7801801 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Molecular basis for protein-protein interactions.

Seychell Brandon Charles BC   Beck Tobias T  

Beilstein journal of organic chemistry 20210104


This minireview provides an overview on the current knowledge of protein-protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein-protein interactions and their molecular interactions is important for a number of applications, including drug design. Protein-protein interactions and their discovery are thus an interesting avenue for understanding how protein complexes, which make up  ...[more]

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