Dataset Information

Lung Ultrasound in the Emergency Department for Early Identification of COVID-19 Pneumonia.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) is a pandemic overwhelming the health care systems worldwide. Lung ultrasound (LUS) use has been proposed to identify suspected COVID-19 patients and direct them to the isolation area in the emergency department (ED) or to discharge them for outpatient treatment.

Objective

Our aim was to retrospectively investigate the use of LUS in the ED to identify COVID-19 pneumonia (CP).

Methods

We performed a retrospective single-center study including all patients accessing the ED who underwent LUS examination for suspicion of COVID-19 during the initial outbreak. Demographics, clinical parameters, laboratory values, imaging features, and outcome variables were collected. The receiver operating characteristic (ROC) curve was used to evaluate diagnostic accuracy.

Results

A total of 41% patients were COVID-19-positive; 67% of them were diagnosed with CP. The ROC curve of the LUS score showed an area under the curve of 0.837 (95% CI 0.75-0.92) and with a cutoff value ?3 identified 28 of 31 patients with CP and 11 of 15 without (sensitivity 90%, 95% CI 74-97%; specificity 75%, 95% CI 56-76%). LUS in combination with nasopharyngeal swab has a sensitivity of 100% (95% CI 74-97%) and a specificity of 61% (95% CI 44-67%).

Conclusions

LUS is a promising technique for early identification of CP in patients who accessed the ED in an active epidemic time. The LUS score shows a sensitivity of 90% for CP, allowing to quickly direct patients with COVID-19 to the ED isolation area or to discharge them for outpatient treatment.

SUBMITTER: Zanforlin A

PROVIDER: S-EPMC7801958 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Publications

Lung Ultrasound in the Emergency Department for Early Identification of COVID-19 Pneumonia.

Zanforlin Alessandro A Strapazzon Giacomo G Falk Markus M Gallina Valentina V Viteritti Antonio A Valzolgher Laura L La Guardia Mario M Ferro Federica F Pagani Leonardo L Vezzali Norberto N

Respiration; international review of thoracic diseases 20201207 2

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) is a pandemic overwhelming the health care systems worldwide. Lung ultrasound (LUS) use has been proposed to identify suspected COVID-19 patients and direct them to the isolation area in the emergency department (ED) or to discharge them for outpatient treatment.<h4>Objective</h4>Our aim was to retrospectively investigate the use of LUS in the ED to identify COVID-19 pneumonia (CP).<h4>Methods</h4>We performed a retrospective single-center s ...[more]

PMID: 33285550

Similar Datasets

Project description:BackgroundChest radiography (CXR) and computerized tomography (CT) are the standard methods for lung imaging in diagnosing COVID-19 pneumonia in the intensive care unit (ICU), despite their limitations. This study aimed to assess the performance of bedside lung ultrasound examination by a critical care physician for the diagnosis of COVID-19 pneumonia during acute admission to the ICU.MethodThis was an observational, prospective, single-center study conducted in the intensive care unit of Adan General Hospital from April 10, 2020, to May 26, 2020. The study included adults with suspicion of COVID-19 Infection who were transferred to the ICU. Patients were admitted to the ICU directly from the ED after reverse transcriptase-polymerase chain reaction (RT-PCR) swabs were sent to the central virology laboratory in Kuwait, and the results were released 16 to 24 hours after the time of admission. A certified intensivist in critical care ultrasound performed the lung ultrasound within 12 hours of the patient's admission to the ICU.The treating physician confirmed the diagnosis of COVID-19 pneumonia based on a set of clinical features, inflammatory markers, biochemical profile studies, RT-PCR test results, and CXR.ResultsOf 77 patients with suspected COVID-19 pneumonia, 65 (84.4%) were confirmed. The median age of the patients was 48 (31-68) years, and 51 (71%) were men.In the group of patients with confirmed COVID-19 pneumonia, LUS revealed four signs suggestive of COVID-19 pneumonia in 63 patients (96.9%) (sensitivity 96.9%, CI 85%-99.5%). Two patients presented with unilateral lobar pneumonia without other ultrasonic signs of COVID-19 pneumonia but with positive RT-PCR results. Among patients in the group without COVID-19 pneumonia who had negative RT-PCR results, 11 (91.7%) were LUS negative for COVID-19 pneumonia (specificity 91.7%, 95% CI 58.72%-99.77%).ConclusionsDuring the COVID-19 outbreak, LUS allows the identification of early signs of interstitial pneumonia. LUS patterns that show a combination of the four major signs offer high sensitivity and specificity compared to nasopharyngeal RT-PCR.

Dataset Information

Lung Ultrasound in the Emergency Department for Early Identification of COVID-19 Pneumonia.

Background

Objective

Methods

Results

Conclusions

Publications

Lung Ultrasound in the Emergency Department for Early Identification of COVID-19 Pneumonia.

Similar Datasets

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