Ontology highlight
ABSTRACT:
SUBMITTER: Soldano A
PROVIDER: S-EPMC7802073 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Soldano Anabel A Yao Huili H Punchi Hewage Achala N D AND Meraz Kevin K Annor-Gyamfi Joel K JK Bunce Richard A RA Battaile Kevin P KP Lovell Scott S Rivera Mario M
ACS infectious diseases 20201203 1
Bacteria depend on a well-regulated iron homeostasis to survive adverse environments. A key component of the iron homeostasis machinery is the compartmentalization of Fe<sup>3+</sup> in bacterioferritin and its subsequent mobilization as Fe<sup>2+</sup> to satisfy metabolic requirements. In <i>Pseudomonas aeruginosa</i> Fe<sup>3+</sup> is compartmentalized in bacterioferritin (BfrB), and its mobilization to the cytosol requires binding of a ferredoxin (Bfd) to reduce the stored Fe<sup>3+</sup> a ...[more]