Effects of family history of diabetes on pancreatic β-cell function and diabetic ketoacidosis in newly diagnosed patients with type 2 diabetes: a cross-sectional study in China.

ABSTRACT:

Objective

To investigate the association between a parental and/or sibling history of diabetes and clinical characteristics.

Design

A cross-sectional study.

Setting

The data were collected from the endocrinology department of The Second Xiangya Hospital of Central South University from June 2017 to October 2019.

Participants

A total of 894 newly diagnosed patients with type 2 diabetes were recruited. Data on clinical characteristics were collected from patient medical records. Pancreatic β-cell function and insulin resistance were calculated with the homeostatic model assessment. SPSS V.25.0 was used to perform the analysis.

Results

The percentages of patients with parental and sibling histories of diabetes were 14.8% and 9.8%, respectively. The prevalen

SUBMITTER: Xiong X 

PROVIDER: S-EPMC7802721 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature