Ontology highlight
ABSTRACT:
SUBMITTER: LaFontaine E
PROVIDER: S-EPMC7804209 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
LaFontaine Ethan E Miller Clare M CM Permaul Natasha N Martin Elliot T ET Fuchs Gabriele G
Virology 20200325
Viruses have evolved strategies to ensure efficient translation using host cell ribosomes and translation factors. In addition to cleaving translation initiation factors required for host cell translation, poliovirus (PV) uses an internal ribosome entry site (IRES). Recent studies suggest that viruses exploit specific ribosomal proteins to enhance translation of their viral proteins. The ribosomal protein receptor for activated C kinase 1 (RACK1), a protein of the 40S ribosomal subunit, was prev ...[more]