Differential effects of sodium chloride and monosodium glutamate on kidney of adult and aging mice.
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ABSTRACT:
SUBMITTER: Celestino M
PROVIDER: S-EPMC7804302 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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Differential effects of sodium chloride and monosodium glutamate on kidney of adult and aging mice.
Celestino Michele M Balmaceda Valdez Valeria V Brun Paola P Castagliuolo Ignazio I Mucignat-Caretta Carla C
Scientific reports 20210112 1
Monosodium Glutamate (MSG) is used as flavour enhancer, with potential beneficial effects due to its nutritional value. Given the decline in kidney functions during aging, we investigated the impact of MSG voluntary intake on the kidney of male mice, aged 6 or 18 months. For 2 months, they freely consumed water (control group), sodium chloride (0.3% NaCl) or MSG (1% MSG) in addition to standard diet. Young animals consuming sodium chloride presented signs of proteinuria, hyperfiltration, enhance ...[more]
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