Ontology highlight
ABSTRACT:
SUBMITTER: Ye Y
PROVIDER: S-EPMC7804428 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Ye Yulan Y Zhang Liping L Hu Tong T Yin Juan J Xu Lijuan L Pang Zhi Z Chen Weichang W
Scientific reports 20210112 1
Increasing evidence suggests that circular RNAs (circRNAs) play critical roles in various pathophysiological activities. However, the role of circRNAs in inflammatory bowel disease (IBD) remains unclear. Here we report the potential roles of hsa_circRNA_103765 in regulating cell apoptosis induced by TNF-α in Crohn's disease (CD). We identify that CircRNA_103765 expression was significantly upregulated in peripheral blood mononuclear cells (PBMCs) of patients with active IBD. A positive correlati ...[more]