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Signatures of conserved and unique molecular features in Afrotheria.


ABSTRACT: Afrotheria is a clade of African-origin species with striking dissimilarities in appearance and habitat. In this study, we compared whole proteome sequences of six Afrotherian species to obtain a broad viewpoint of their underlying molecular make-up, to recognize potentially unique proteomic signatures. We find that 62% of the proteomes studied here, predominantly involved in metabolism, are orthologous, while the number of homologous proteins between individual species is as high as 99.5%. Further, we find that among Afrotheria, L. africana has several orphan proteins with 112 proteins showing?

SUBMITTER: Yazhini A 

PROVIDER: S-EPMC7806701 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Signatures of conserved and unique molecular features in Afrotheria.

Yazhini Arangasamy A   Srinivasan Narayanaswamy N   Sandhya Sankaran S  

Scientific reports 20210113 1


Afrotheria is a clade of African-origin species with striking dissimilarities in appearance and habitat. In this study, we compared whole proteome sequences of six Afrotherian species to obtain a broad viewpoint of their underlying molecular make-up, to recognize potentially unique proteomic signatures. We find that 62% of the proteomes studied here, predominantly involved in metabolism, are orthologous, while the number of homologous proteins between individual species is as high as 99.5%. Furt  ...[more]

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