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Omega-7 oil increases telomerase activity and accelerates healing of grafted burn and donor site wounds.


ABSTRACT: This study investigated the efficacy of Omega-7 isolated from the sea buckthorn oil (Polyvit Co., Ltd, Gangar Holding, Ulaanbaatar, Mongolia) in ovine burn wound healing models. In vitro, proliferation (colony-forming rate) and migration (scratch) assays using cultured primary ovine keratinocytes were performed with or without 0.025% and 0.08% Omega-7, respectively. The colony-forming rate of keratinocytes in the Omega-7 group at 72 and 96 h were significantly higher than in the control (P?

SUBMITTER: Niimi Y 

PROVIDER: S-EPMC7806965 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Omega-7 oil increases telomerase activity and accelerates healing of grafted burn and donor site wounds.

Niimi Yosuke Y   Pérez-Bello Dannelys D   Ihara Koji K   Fukuda Satoshi S   Jacob Sam S   Andersen Clark R CR   Baljinnyam Tuvshintugs T   Kim Jisoo J   Alharbi Suzan S   Prough Donald S DS   Enkhbaatar Perenlei P  

Scientific reports 20210113 1


This study investigated the efficacy of Omega-7 isolated from the sea buckthorn oil (Polyvit Co., Ltd, Gangar Holding, Ulaanbaatar, Mongolia) in ovine burn wound healing models. In vitro, proliferation (colony-forming rate) and migration (scratch) assays using cultured primary ovine keratinocytes were performed with or without 0.025% and 0.08% Omega-7, respectively. The colony-forming rate of keratinocytes in the Omega-7 group at 72 and 96 h were significantly higher than in the control (P < 0.0  ...[more]

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