Dataset Information

A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer.

ABSTRACT:

Background and purpose

Adjuvant radiation therapy (RT) of the whole breast (WB) is still the standard treatment for early breast cancer. A variety of radiation techniques is currently available according to different delivery strategies. This study aims to provide a comparison of six treatment planning strategies commonly adopted for breast-conserving adjuvant RT and to use the Pareto concept in an attempt to assess the degree of plan optimization.

Materials and methods

Two groups of six left- and five right-sided cases with different dose prescriptions were involved (22 patients in total). Field-in-Field (FiF), two and four Fields static-IMRT (sIMRT-2f and sIMRT-4f), Volumetric-Modulated-Arc-Therapy (VMAT), Helical Tomotherapy (HT) and Static-Angles Tomotherapy (TomoDirect™ - TD) were planned. Dose volume constraints were taken from the RTOG protocol 1005. Pareto fronts were built for a selected case to evaluate the reliability of the plan optimization process.

Results

The best target dose coverage was observed for TD able to improve significantly (p?ConclusionsOverall, TD provided significantly better results in terms of target coverage and dose sparing of ipsilateral lung with respect to all other evaluated techniques. It also significantly minimized dose to contralateral breast together with FiF. Pareto front analysis confirmed the reliability of the optimization for a selected case.

SUBMITTER: Zeverino M

PROVIDER: S-EPMC7807600 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Publications

A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer.

Zeverino Michele M Petersson Kristoffer K Kyroudi Archonteia A Jeanneret-Sozzi Wendy W Bourhis Jean J Bochud Francois F Moeckli Raphael R

Physics and imaging in radiation oncology 20180701

<h4>Background and purpose</h4>Adjuvant radiation therapy (RT) of the whole breast (WB) is still the standard treatment for early breast cancer. A variety of radiation techniques is currently available according to different delivery strategies. This study aims to provide a comparison of six treatment planning strategies commonly adopted for breast-conserving adjuvant RT and to use the Pareto concept in an attempt to assess the degree of plan optimization.<h4>Materials and methods</h4>Two groups ...[more]

PMID: 33458403

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Dataset Information

A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer.

Background and purpose

Materials and methods

Results

Publications

A treatment planning comparison of contemporary photon-based radiation techniques for breast cancer.

Similar Datasets

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