Ontology highlight
ABSTRACT:
SUBMITTER: Deng S
PROVIDER: S-EPMC7807753 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Deng Shaoxin S Cui Cheng-Xing CX Duan Lingyao L Hu Linfeng L Yang Xiaoxun X Wang Ji-Chao JC Qu Ling-Bo LB Zhang Yuping Y
ACS omega 20201229 1
Targeted release of anticancer drugs to tumor sites has a pivotal role in clinical oncology. pH-responsive drug delivery systems, with an intelligent and targeted release of anticancer drugs in a controllable manner based on sensitivities to the weakly acidic environments of tumor cellular microenvironments, are desirable. Herein, the design of such a pH-responsive drug delivery system is detailed using in situ amino-functionalized hollow mesoporous silica nanoparticles as carriers. The drug rel ...[more]