Ontology highlight
ABSTRACT:
SUBMITTER: de la Arada I
PROVIDER: S-EPMC7809034 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
de la Arada Igor I Torralba Johana J Tascón Igor I Colom Adai A Ubarretxena-Belandia Iban I Arrondo José L R JLR Apellániz Beatriz B Nieva José L JL
Scientific reports 20210114 1
Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction. Conserved sequences rich in aromatic residues juxtaposed to the external leaflet of the virion-wrapping membranes are also frequently found in viral fusion glycoproteins. These membrane-proximal external regions (MPERs) have been implicated in the promotion of the viral membran ...[more]