Group and individual level variations between symmetric and asymmetric DLPFC montages for tDCS over large scale brain network nodes.

ABSTRACT: Two challenges to optimizing transcranial direct current stimulation (tDCS) are selecting between, often similar, electrode montages and accounting for inter-individual differences in response. These two factors are related by how tDCS montage determines current flow through the brain considered across or within individuals. MRI-based computational head models (CHMs) predict how brain anatomy determines electric field (EF) patterns for a given tDCS montage. Because conventional tDCS produces diffuse brain current flow, stimulation outcomes may be understood as modulation of global networks. Therefore, we developed a network-led, rather than region-led, approach. We specifically considered two common "frontal" tDCS montages that nominally target the dorsolateral prefrontal cortex; asymmetri

SUBMITTER: Soleimani G 

PROVIDER: S-EPMC7809198 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature