Ontology highlight
ABSTRACT:
SUBMITTER: Ritzau-Jost A
PROVIDER: S-EPMC7809622 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Ritzau-Jost Andreas A Tsintsadze Timur T Krueger Martin M Ader Jonas J Bechmann Ingo I Eilers Jens J Barbour Boris B Smith Stephen M SM Hallermann Stefan S
Cell reports 20210101 2
Presynaptic action potential spikes control neurotransmitter release and thus interneuronal communication. However, the properties and the dynamics of presynaptic spikes in the neocortex remain enigmatic because boutons in the neocortex are small and direct patch-clamp recordings have not been performed. Here, we report direct recordings from boutons of neocortical pyramidal neurons and interneurons. Our data reveal rapid and large presynaptic action potentials in layer 5 neurons and fast-spikin ...[more]