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Morbidity associated with patent ductus arteriosus in preterm newborns: a retrospective case-control study.


ABSTRACT:

Introduction

Association between persistency of a patent ductus arteriosus (PDA) and morbidity in preterm newborns is still controversial. We aimed to investigate the relation between PDA and morbidity in a large retrospective study.

Methods

A case-control study including neonates consecutively admitted to the Neonatal Intensive Care Unit (NICU), with gestational age (GA)?ResultsWe enrolled 85 Cases and 193 Controls. Subjects with hs-PDA had significantly (p?ConclusionsOccurrence of the main morbidities of prematurity depended by hs-PDA, in association with GA, BW, and use of prenatal steroids. In extremely premature babies, hs-PDA is a risk factor for BPD, one of the most important morbidity of prematurity, independently by other confounding variables.

SUBMITTER: Terrin G 

PROVIDER: S-EPMC7809822 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Morbidity associated with patent ductus arteriosus in preterm newborns: a retrospective case-control study.

Terrin Gianluca G   Di Chiara Maria M   Boscarino Giovanni G   Metrangolo Valentina V   Faccioli Francesca F   Onestà Elisa E   Giancotti Antonella A   Di Donato Violante V   Cardilli Viviana V   De Curtis Mario M  

Italian journal of pediatrics 20210114 1


<h4>Introduction</h4>Association between persistency of a patent ductus arteriosus (PDA) and morbidity in preterm newborns is still controversial. We aimed to investigate the relation between PDA and morbidity in a large retrospective study.<h4>Methods</h4>A case-control study including neonates consecutively admitted to the Neonatal Intensive Care Unit (NICU), with gestational age (GA) < 32 weeks or body birth weight (BW) < 1500 g, over a 5-year period. Newborns were divided into Cases and Cont  ...[more]

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