Ontology highlight
ABSTRACT:
SUBMITTER: Hartmann W
PROVIDER: S-EPMC7810711 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Hartmann Wiebke W Blankenhaus Birte B Brunn Marie-Luise ML Meiners Jana J Breloer Minka M
Scientific reports 20210115 1
Helminths are large multicellular parasites that infect one quarter of the human population. To prolong their survival, helminths suppress the immune responses of their hosts. Strongyloides ratti delays its expulsion from the gut by induction of regulatory circuits in a mouse strain-specific manner: depletion of Foxp3<sup>+</sup> regulatory T cells (Treg) improves the anti-S. ratti immunity in BALB/c but not in C57BL/6 mice. In the current study we compare the hierarchy of immunoregulatory pathw ...[more]