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Premature ventricular contraction is associated with increased risk of atrial fibrillation: a nationwide population-based study.


ABSTRACT: Premature ventricular contraction (PVC) and atrial fibrillation (AF) are common arrhythmias affecting 1-2% of the general population. During PVC, retrograde ventriculo-atrial activation can occur and act like an atrial ectopy. However, the clinical significance of this phenomenon is not fully understood. We aimed to elucidate whether the clinical diagnosis of PVC can increase the risk of new-onset AF. We performed a nationwide population-based analysis using the Korean National Health Insurance Service database. A total of 9,537,713 people without prior history of PVC and AF were identified. Among these people, 4135 developed PVC in 2009, and people with and without PVC were followed until 2018. People who had PVC showed an increased risk of new-onset AF as compared with people without PVC (hazard ratio [HR]?=?2.705; 95% confidence interval [CI]?=?2.428-3.013; p?

SUBMITTER: Kim YG 

PROVIDER: S-EPMC7810887 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Premature ventricular contraction is associated with increased risk of atrial fibrillation: a nationwide population-based study.

Kim Yun Gi YG   Han Kyung-Do KD   Choi Jong-Il JI   Choi Yun Young YY   Choi Ha Young HY   Shim Jaemin J   Kim Young-Hoon YH  

Scientific reports 20210115 1


Premature ventricular contraction (PVC) and atrial fibrillation (AF) are common arrhythmias affecting 1-2% of the general population. During PVC, retrograde ventriculo-atrial activation can occur and act like an atrial ectopy. However, the clinical significance of this phenomenon is not fully understood. We aimed to elucidate whether the clinical diagnosis of PVC can increase the risk of new-onset AF. We performed a nationwide population-based analysis using the Korean National Health Insurance  ...[more]

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