Ontology highlight
ABSTRACT:
SUBMITTER: Xiong Y
PROVIDER: S-EPMC7810960 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Xiong Yao Y Wang Yan Y Ma Ling L Zhang Ying Y Qu Xinlan X Huang Lei L Wen Xue X Liu Huimin H Zhang Ming M Zhang Yuanzhen Y
Journal of cellular and molecular medicine 20201117 1
Studies have reported that non-receptive endometrium or abnormal decidualization was closely related to recurrent implantation failure (RIF). MLL1 is a histone H3 lysine 4 trimethylation (H3K4me3) transferase that regulates the transcriptional activation of target genes. The role of MLL1 has been underexplored during decidualization. In our research, we found the expression of MLL1 was closely related to endometrial receptivity, and it was responsible to hormone stimulation. Inhibiting the funct ...[more]