Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts.
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ABSTRACT:
SUBMITTER: Oami T
PROVIDER: S-EPMC7810989 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts.
Oami Takehiko T Karasawa Satoshi S Shimada Tadanaga T Nakada Taka-Aki TA Abe Toshikazu T Ogura Hiroshi H Shiraishi Atsushi A Kushimoto Shigeki S Saitoh Daizoh D Fujishima Seitaro S Mayumi Toshihiko T Shiino Yasukazu Y Tarui Takehiko T Hifumi Toru T Otomo Yasuhiro Y Okamoto Kohji K Umemura Yutaka Y Kotani Joji J Sakamoto Yuichiro Y Sasaki Junichi J Shiraishi Shin-Ichiro SI Takuma Kiyotsugu K Tsuruta Ryosuke R Hagiwara Akiyoshi A Yamakawa Kazuma K Masuno Tomohiko T Takeyama Naoshi N Yamashita Norio N Ikeda Hiroto H Ueyama Masashi M Fujimi Satoshi S Gando Satoshi S
Scientific reports 20210115 1
Current research regarding the association between body mass index (BMI) and altered clinical outcomes of sepsis in Asian populations is insufficient. We investigated the association between BMI and clinical outcomes using two Japanese cohorts of severe sepsis (derivation cohort, Chiba University Hospital, n = 614; validation cohort, multicenter cohort, n = 1561). Participants were categorized into the underweight (BMI < 18.5) and non-underweight (BMI ≥ 18.5) groups. The primary outcome was 28-d ...[more]
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