Ontology highlight
ABSTRACT:
SUBMITTER: Ding Y
PROVIDER: S-EPMC7812269 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Ding Yanting Y Xia Sijing S Zhang Han H Chen Qin Q Niu Bing B
Journal of cellular and molecular medicine 20201210 2
Loureirin B (LB) is a natural product derived from Sanguis draconis, which has hypoglycaemic effects. In order to research the possible target of LB in the treatment of diabetes, molecular docking was used to simulate the interaction between LB and potential targets, and among them, glucagon-like peptide-1 receptor (GLP-1R) had the optimal results. Further, spectroscopy and surface plasmon resonance (SPR) experiments were applied to detect the interaction between LB and GLP-1R. Ultimately, after ...[more]