Ontology highlight
ABSTRACT:
SUBMITTER: Li M
PROVIDER: S-EPMC7812295 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Li Ming M Li Ming M Liu Jingwen J Liu Dong D Duan Xuchu X Zhang Qingchen Q Wang Dawei D Zheng Qingyin Q Bai Xiaohui X Lu Zhiming Z
Journal of cellular and molecular medicine 20201203 2
Exposure to ototoxic drugs is a significant cause of hearing loss that affects about 30 thousand children with potentially serious physical, social and psychological dysfunctions every year. Cisplatin (CP) and aminoglycosides are effective antineoplastic or bactericidal drugs, and their application has a high probability of ototoxicity which results from the death of hair cells (HCs). Here, we describe the therapeutic effect of the flavonoid compound naringin (Nar) against ototoxic effects of ci ...[more]