Ontology highlight
ABSTRACT:
SUBMITTER: Smith BAH
PROVIDER: S-EPMC7812346 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Smith Benjamin A H BAH Bertozzi Carolyn R CR
Nature reviews. Drug discovery 20210118 3
Carbohydrates - namely glycans - decorate every cell in the human body and most secreted proteins. Advances in genomics, glycoproteomics and tools from chemical biology have made glycobiology more tractable and understandable. Dysregulated glycosylation plays a major role in disease processes from immune evasion to cognition, sparking research that aims to target glycans for therapeutic benefit. The field is now poised for a boom in drug development. As a harbinger of this activity, glycobiology ...[more]