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A study on episodic memory reconsolidation that tells us more about consolidation.

ABSTRACT: Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen "delayed" effect of quiescence on consolidation. Our findings reveal that the beneficial effect of quiescence on episodic memory consolidation is not restricted to immediately following encoding but can be achieved at a delayed stage and even following a period of task engagement.

SUBMITTER: Craig M

PROVIDER: S-EPMC7812862 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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A study on episodic memory reconsolidation that tells us more about consolidation.

Craig Michael M Knowles Christopher C Hill Stephanie S Dewar Michaela M

Learning & memory (Cold Spring Harbor, N.Y.) 20210115 2

Awake quiescence immediately after encoding is conducive to episodic memory consolidation. Retrieval can render episodic memories labile again, but reconsolidation can modify and restrengthen them. It remained unknown whether awake quiescence after retrieval supports episodic memory reconsolidation. We sought to examine this question via an object-location memory paradigm. We failed to probe the effect of quiescence on reconsolidation, but we did observe an unforeseen "delayed" effect of quiesce ...[more]

PMID: 33452111

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