Ontology highlight
ABSTRACT:
SUBMITTER: Fu H
PROVIDER: S-EPMC7814030 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Nature communications 20210118 1
There have been notable advances in the development of vaccines against active tuberculosis (TB) disease for adults and adolescents. Using mathematical models, we seek to estimate the potential impact of a post-exposure TB vaccine, having 50% efficacy in reducing active disease, on global rifampicin-resistant (RR-) TB burden. In 30 countries that together accounted for 90% of global RR-TB incidence in 2018, a future TB vaccine could avert 10% (95% credible interval: 9.7-11%) of RR-TB cases and 7 ...[more]