Ontology highlight
ABSTRACT:
SUBMITTER: Devaraj A
PROVIDER: S-EPMC7815147 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Devaraj Aishwarya A González Juan F JF Eichar Bradley B Thilliez Gatan G Kingsley Robert A RA Baker Stephen S Allard Marc W MW Bakaletz Lauren O LO Gunn John S JS Goodman Steven D SD
PLoS pathogens 20210119 1
Salmonella Typhi is the primary causative agent of typhoid fever; an acute systemic infection that leads to chronic carriage in 3-5% of individuals. Chronic carriers are asymptomatic, difficult to treat and serve as reservoirs for typhoid outbreaks. Understanding the factors that contribute to chronic carriage is key to development of novel therapies to effectively resolve typhoid fever. Herein, although we observed no distinct clustering of chronic carriage isolates via phylogenetic analysis, w ...[more]