Unknown

Dataset Information

0

Long-Term Clinical Outcomes of Unprotected Left Main Percutaneous Coronary Intervention: A Large Single-Centre Experience.


ABSTRACT:

Aims

This study sought to report the 10-year clinical outcomes of patients who underwent unprotected left main (LM) percutaneous coronary intervention (PCI) in a large centre.

Methods and results

A total of 913 consecutive patients who underwent unprotected LM PCI from January 2004 to December 2008 at Fu Wai Hospital were retrospectively analysed; the mean age was 60.0?±?10.9 years, females accounted for 22% of patients, diabetes was present in 27.7% of patients, and an LM bifurcation lesion occurred in 82.9% of patients. During the median follow-up of 9.7 years, major adverse cardiac or cerebrovascular events (MACCEs) occurred in 25.6% (234) of patients, and the rates of all-cause death, myocardial infarction, and stroke were 14.9%, 11.0%, and 7.1%, respectively. Cardiac death occurred in only 7.9% of patients. The estimated event rate was 41.9% for death/myocardial infarction/any revascularization and 45.9% for death/MI/stroke/any revascularization. Definite/probable stent thrombosis occurred in 4.3% (39) of patients. According to the subgroup analysis, IVUS-guided PCI was associated with less long-term MACCEs. Further multivariate analysis identified that age and LVEF<40% were the only independent predictors for 10-year death. Age, LVEF<40%, creatinine clearance, and incomplete revascularization were independent predictors for death/MI, while a two-stent strategy, diabetes, a transradial approach, and the use of bare metal stents (BMSs) or first-generation drug-eluting stents (DESs) were not.

Conclusions

Unprotected LM PCI in a large cohort of consecutive patients in a single large centre demonstrated favourable long-term outcomes up to 10 years even with the use of BMSs and first-generation of DESs.

SUBMITTER: Gao L 

PROVIDER: S-EPMC7815387 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

altmetric image

Publications

Long-Term Clinical Outcomes of Unprotected Left Main Percutaneous Coronary Intervention: A Large Single-Centre Experience.

Gao Lijian L   Gao Zhan Z   Song Ying Y   Guan Changdong C   Xu Bo B   Chen Jue J   Liu Haibo H   Qin Xuewen X   Yao Min M   Yuan Jinqing J   Wu Yongjian Y   Hu Fenghuan F   Qian Jie J   Tang Yida Y   Dou Kefei K   Yang Weixian W   Qiu Hong H   Mu Chaowei C   Dai Jun J   Qiao Shubin S   Chen Jilin J   Gao Runlin R   Yang Yuejin Y  

Journal of interventional cardiology 20210112


<h4>Aims</h4>This study sought to report the 10-year clinical outcomes of patients who underwent unprotected left main (LM) percutaneous coronary intervention (PCI) in a large centre.<h4>Methods and results</h4>A total of 913 consecutive patients who underwent unprotected LM PCI from January 2004 to December 2008 at Fu Wai Hospital were retrospectively analysed; the mean age was 60.0 ± 10.9 years, females accounted for 22% of patients, diabetes was present in 27.7% of patients, and an LM bifurca  ...[more]

Similar Datasets

| S-EPMC9075483 | biostudies-literature
| S-EPMC5443793 | biostudies-literature
| S-EPMC4276481 | biostudies-literature
| S-EPMC5489169 | biostudies-literature
| S-EPMC5808470 | biostudies-literature
| S-EPMC5839846 | biostudies-other
| S-EPMC9627854 | biostudies-literature
| S-EPMC10331562 | biostudies-literature
| S-EPMC10011221 | biostudies-literature