Cumulative burden of metabolic syndrome and its components on the risk of atrial fibrillation: a nationwide population-based study.

ABSTRACT:

Background

The metabolic syndrome (MetS) and its components are associated with the development of atrial fibrillation (AF). However, the impact of time-burden of MetS on the risk of AF is unknown. We investigated the effect of the cumulative longitudinal burden of MetS on the development of AF.

Methods

We included 2 885 189 individuals without AF who underwent four annual health examinations during 2009-2013 from the database of the Korean national health insurance service. Metabolic burdens were evaluated in the following three ways: (1) cumulative number of MetS diagnosed at each health examination (0-4 times); (2) cumulative number of each MetS component diagnosed at each health examination (0-4 times per MetS component); and (3) cumulative number of total MetS component

SUBMITTER: Ahn HJ 

PROVIDER: S-EPMC7816376 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature