Ontology highlight
ABSTRACT:
SUBMITTER: Zhou L
PROVIDER: S-EPMC7817116 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Zhou Lili L Miller Caitlyn C Miraglia Loren J LJ Romero Angelica A Mure Ludovic S LS Panda Satchidananda S Kay Steve A SA
Proceedings of the National Academy of Sciences of the United States of America 20210101 1
The regulatory mechanisms of circadian rhythms have been studied primarily at the level of the transcription-translation feedback loops of protein-coding genes. Regulatory modules involving noncoding RNAs are less thoroughly understood. In particular, emerging evidence has revealed the important role of microRNAs (miRNAs) in maintaining the robustness of the circadian system. To identify miRNAs that have the potential to modulate circadian rhythms, we conducted a genome-wide miRNA screen using U ...[more]