Risk assessment in precapillary pulmonary hypertension: a comparative analysis.

ABSTRACT:

Background

Risk stratification is essential to assess mortality risk and guide treatment in patients with precapillary pulmonary hypertension (PH). We herein compared the accuracy of different currently used PH risk stratification tools and evaluated the significance of particular risk parameters.

Methods

We conducted a retrospective longitudinal observational cohort study evaluating seven different risk assessment approaches according to the current PH guidelines. A comprehensive assessment including multi-parametric risk stratification was performed at baseline and 4 yearly follow-up time-points. Multi-step Cox hazard analysis was used to analyse and refine risk prediction.

Results

Various available risk models effectively predicted mortality in patients with precap

SUBMITTER: Sonnweber T 

PROVIDER: S-EPMC7818775 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature