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ABSTRACT: Background
Peutz-Jeghers syndrome (PJS) is a very rare autosomal dominant genetic disorder characterized by hamartomatous polyps in the gastrointestinal tract and hyperpigmentation of the lips, hands, and feet. The hamartomatous polyps in the small intestine often cause intussusception and bleeding.Case presentation
A 62-year-old male was hospitalized for treatment of deep vein thrombosis and pulmonary embolism. In the small intestine, computed tomography showed three small polyps with intussusceptions. Since the patient had gastrointestinal polyposis and pigmentation of his lips, fingers, and toes, he was diagnosed with PJS. After an inferior vena cava filter was placed, he underwent laparoscopic-assisted surgery. The polyps causing intussusception were resected as far as possible without intestinal resection, since they had caused progressive anemia and might cause intestinal obstruction in the future. The patient was discharged from the hospital on postoperative day 9 without complications.Conclusions
Laparoscopic-assisted disinvagination and polypectomy is a useful, minimally invasive treatment for multiple intussusceptions caused by small intestinal polyps in patients with PJS.
SUBMITTER: Yamamoto M
PROVIDER: S-EPMC7819471 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Yamamoto Masaaki M Iwamoto Kazuya K Suzuki Rei R Mukai Yosuke Y Takeoka Tomohira T Asukai Kei K Shinno Naoki N Hara Hisashi H Kanemura Takashi T Nakai Nozomu N Hasegawa Shinichiro S Sugimura Keijiro K Haraguchi Naotsugu N Nishimura Junichi J Wada Hiroshi H Takahashi Hidenori H Matsuda Chu C Yasui Masayoshi M Omori Takeshi T Miyata Hiroshi H Ohue Masayuki M Murata Masaru M
World journal of surgical oncology 20210121 1
<h4>Background</h4>Peutz-Jeghers syndrome (PJS) is a very rare autosomal dominant genetic disorder characterized by hamartomatous polyps in the gastrointestinal tract and hyperpigmentation of the lips, hands, and feet. The hamartomatous polyps in the small intestine often cause intussusception and bleeding.<h4>Case presentation</h4>A 62-year-old male was hospitalized for treatment of deep vein thrombosis and pulmonary embolism. In the small intestine, computed tomography showed three small polyp ...[more]