Unknown

Dataset Information

0

Precision Medicine in Pediatric Oncology.


ABSTRACT: Improvements in outcome have been seen in children and adolescents with cancer. Nevertheless, challenges remain in trying to improve the outcomes for all children diagnosed with cancer, particularly in patients with metastatic disease or with cancers that are resistant or recur after standard treatment. Precision medicine trials using individualized tumor molecular profiling for selection of targeted therapies are ongoing in adult malignancies. Similar approaches are being applied to children and adolescents with cancer. This article describes how precision medicine is being applied to pediatric oncology and the unique challenges being faced with these efforts.

SUBMITTER: Vo KT 

PROVIDER: S-EPMC7819485 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Precision Medicine in Pediatric Oncology.

Vo Kieuhoa T KT   Parsons D Williams DW   Seibel Nita L NL  

Surgical oncology clinics of North America 20191029 1


Improvements in outcome have been seen in children and adolescents with cancer. Nevertheless, challenges remain in trying to improve the outcomes for all children diagnosed with cancer, particularly in patients with metastatic disease or with cancers that are resistant or recur after standard treatment. Precision medicine trials using individualized tumor molecular profiling for selection of targeted therapies are ongoing in adult malignancies. Similar approaches are being applied to children an  ...[more]

Similar Datasets

| S-EPMC6119176 | biostudies-other
| S-EPMC5770114 | biostudies-literature
| S-EPMC5683396 | biostudies-literature
| S-EPMC9570321 | biostudies-literature
| S-EPMC9913103 | biostudies-literature
| S-EPMC6934769 | biostudies-literature
| S-EPMC4955753 | biostudies-literature
| S-EPMC4910693 | biostudies-literature
| S-EPMC5650957 | biostudies-literature
| S-EPMC8667861 | biostudies-literature