Dataset Information

Evaluation of embryonic posture using four-dimensional ultrasound and virtual reality.

ABSTRACT:

Aim

To assess the possibility of embryonic posture evaluation (=feasibility, reproducibility, variation) at rest at 9?weeks' (+0-6?days) gestational age (GA) using four-dimensional ultrasound and virtual reality (VR) techniques. Moreover, it is hypothesized that embryonic posture shows variation at the same time point in an uneventful pregnancy.

Methods

In this explorative prospective cohort study, 23 pregnant women were recruited from the Rotterdam periconceptional cohort. A transvaginal four-dimensional ultrasound examination of 30?min per pregnancy was performed between 9 and 10?weeks' GA. The acquired datasets were offline evaluated longitudinally (i.e. per frame) using VR techniques.

Results

The ultrasound data of 16 (70%) out of 23 pregnancies were eligible for evaluation. At rest the analysis of the embryonic posture was feasible and showed a strong (>80%) intraobserver and interobserver reproducibility for most body parts. The majority of the body parts were in similar anatomic positions at rest. However, variations in anatomic positions (e.g. 6% rotated head, 9% laterally bent spine), within and between embryos, were seen at 9?weeks' GA.

Conclusion

In this unique study, we showed for the first time that embryonic posture measurements at rest can be performed in a reliable way using state-of-the-art four-dimensional ultrasound and VR techniques. Already early in prenatal life there are differences regarding posture within and between embryos.

SUBMITTER: Frudiger A

PROVIDER: S-EPMC7821160 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Evaluation of embryonic posture using four-dimensional ultrasound and virtual reality.

Frudiger Anne A Mulders Annemarie G M G J AGMGJ Rousian Melek M Plasschaert Sophie C N SCN Koning Anton H J AHJ Willemsen Sten P SP Steegers-Theunissen Regine P M RPM de Vries Johanna I P JIP Steegers Eric A P EAP

The journal of obstetrics and gynaecology research 20201103 1

<h4>Aim</h4>To assess the possibility of embryonic posture evaluation (=feasibility, reproducibility, variation) at rest at 9 weeks' (+0-6 days) gestational age (GA) using four-dimensional ultrasound and virtual reality (VR) techniques. Moreover, it is hypothesized that embryonic posture shows variation at the same time point in an uneventful pregnancy.<h4>Methods</h4>In this explorative prospective cohort study, 23 pregnant women were recruited from the Rotterdam periconceptional cohort. A tran ...[more]

PMID: 33145949

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Project description:The objective of this study was to investigate the feasibility of examining the fetal heart with Tomographic Ultrasound Imaging (TUI) using four-dimensional (4D) volume datasets acquired with spatiotemporal image correlation (STIC).One hundred and ninety-five fetuses underwent 4D ultrasonography (US) of the fetal heart with STIC. Volume datasets were acquired with B-mode (n=195) and color Doppler imaging (CDI) (n=168), and were reviewed offline using TUI, a new display modality that automatically slices 3D/4D volume datasets, providing simultaneous visualization of up to eight parallel planes in a single screen. Visualization rates for standard transverse planes used to examine the fetal heart were calculated and compared for volumes acquired with B-mode or CDI. Diagnoses by TUI were compared to postnatal diagnoses.(1) The four- and five-chamber views and the three-vessel and trachea view were visualized in 97.4% (190/195), 88.2% (172/195), and 79.5% (142/195), respectively, of the volume datasets acquired with B-mode; (2) these views were visualized in 98.2% (165/168), 97.0% (163/168), and 83.6% (145/168), respectively, of the volume datasets acquired with CDI; (3) CDI contributed additional diagnostic information to 12.5% (21/168), 14.2% (24/168) and 10.1% (17/168) of the four- and five-chamber and the three-vessel and trachea views; (4) cardiac anomalies other than isolated ventricular septal defects were identified by TUI in 16 of 195 fetuses (8.2%) and, among these, CDI provided additional diagnostic information in 5 (31.3%); (5) the sensitivity, specificity, positive- and negative-predictive values of TUI to diagnose congenital heart disease in cases where both B-mode and CDI volume datasets were acquired prenatally were 92.9%, 98.8%, 92.9% and 98.8%, respectively.Standard transverse planes commonly used to examine the fetal heart can be automatically displayed with TUI in the majority of fetuses undergoing 4D US with STIC. Due to the retrospective nature of this study, the results should be interpreted with caution and independently confirmed before this methodology is introduced into clinical practice.

Dataset Information

Evaluation of embryonic posture using four-dimensional ultrasound and virtual reality.

Aim

Methods

Results

Conclusion

Publications

Evaluation of embryonic posture using four-dimensional ultrasound and virtual reality.

Similar Datasets

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