European Registry on Helicobacter pylori Management: Effectiveness of First and Second-Line Treatment in Spain.

ABSTRACT: The management of Helicobacter pylori infection has to rely on previous local effectiveness due to the geographical variability of antibiotic resistance. The aim of this study was to evaluate the effectiveness of first and second-line H. pylori treatment in Spain, where the empirical prescription is recommended. A multicentre prospective non-interventional registry of the clinical practice of European gastroenterologists concerning H. pylori infection (Hp-EuReg) was developed, including patients from 2013 until June 2019. Effectiveness was evaluated descriptively and through a multivariate analysis concerning age, gender, presence of ulcer, proton-pump inhibitor (PPI) dose, therapy duration and compliance. Overall, 53 Spanish hospitals were included, and 10,267 patient

SUBMITTER: Caldas M 

PROVIDER: S-EPMC7823881 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature