Dataset Information

Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer.

ABSTRACT:

Background

Postoperative complications have been linked to the morbidity and mortality of several cancers. However, predicting whether complications will occur in the early period after surgery or not is challenging. Hence, this study aimed to examine the diagnostic accuracy of serum creatine phosphokinase (CPK) and c-reactive protein (CRP) in predicting the development of postgastrectomy complications.

Methods

We retrospectively analyzed 188 patients with gastric cancer (GC) who underwent gastrectomy. The diagnostic accuracy of serum CPK and CRP was investigated using the areas under the curves (AUC). The CPK ratio was defined as the CPK on postoperative day (POD) 1 to the CPK on a preoperative day.

Results

Out of 188 patients, 48 (25.5%) developed postoperative complications. The complications group had a greater operative time (p?=?0.037), higher CPK ratio on POD1 (p?ConclusionThe CPK ratio on POD1 and the CRP on POD3 after gastrectomy for GC were predictive factors for complication development and may be employed to prevent the development of such complications and improve the prognosis of patients with GC.

SUBMITTER: Okubo K

PROVIDER: S-EPMC7825180 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer.

Okubo Keishi K Arigami Takaaki T Matsushita Daisuke D Kijima Takashi T Shimonosono Masataka M Uenosono Yoshikazu Y Yanagita Shigehiro S Kurahara Hiroshi H Mori Shinichiro S Ohtsuka Takao T Natsugoe Shoji S

BMC cancer 20210123 1

<h4>Background</h4>Postoperative complications have been linked to the morbidity and mortality of several cancers. However, predicting whether complications will occur in the early period after surgery or not is challenging. Hence, this study aimed to examine the diagnostic accuracy of serum creatine phosphokinase (CPK) and c-reactive protein (CRP) in predicting the development of postgastrectomy complications.<h4>Methods</h4>We retrospectively analyzed 188 patients with gastric cancer (GC) who ...[more]

PMID: 33485312

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Dataset Information

Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer.

Background

Methods

Results

Publications

Clinical impact of creatine phosphokinase and c-reactive protein as predictors of postgastrectomy complications in patients with gastric cancer.

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