Ontology highlight
ABSTRACT:
SUBMITTER: Abid HZ
PROVIDER: S-EPMC7826249 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Abid Heba Z HZ Young Eleanor E McCaffrey Jennifer J Raseley Kaitlin K Varapula Dharma D Wang Hung-Yi HY Piazza Danielle D Mell Joshua J Xiao Ming M
Nucleic acids research 20210101 2
Whole-genome mapping technologies have been developed as a complementary tool to provide scaffolds for genome assembly and structural variation analysis (1,2). We recently introduced a novel DNA labeling strategy based on a CRISPR-Cas9 genome editing system, which can target any 20bp sequences. The labeling strategy is specifically useful in targeting repetitive sequences, and sequences not accessible to other labeling methods. In this report, we present customized mapping strategies that extend ...[more]