Ontology highlight
ABSTRACT:
SUBMITTER: Wilhelm R
PROVIDER: S-EPMC7828274 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Cancers 20210113 2
Cutaneous T cell lymphomas (CTCLs) represent a heterogeneous group of T cell lymphomas that primarily affect the skin. The most frequent forms of CTCL are mycosis fungoides and Sézary syndrome. Both are characterized by frequent recurrence, developing chronic conditions and high mortality with a lack of a curative treatment. In this study, we evaluated the effect of short-chain, cell-permeable C6 Ceramide (C6Cer) on CTCL cell lines and keratinocytes. C6Cer significantly reduced cell viability of ...[more]