Novel Tyrosine Kinase Targets in Urothelial Carcinoma.
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ABSTRACT:
SUBMITTER: Torres-Jimenez J
PROVIDER: S-EPMC7828553 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Novel Tyrosine Kinase Targets in Urothelial Carcinoma.
Torres-Jiménez Javier J Albarrán-Fernández Víctor V Pozas Javier J Román-Gil María San MS Esteban-Villarrubia Jorge J Carrato Alfredo A Rosero Adriana A Grande Enrique E Alonso-Gordoa Teresa T Molina-Cerrillo Javier J
International journal of molecular sciences 20210113 2
Urothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the advanced disease was based on chemotherapy for decades, the developments of different therapies, such as immune checkpoint inhibitors, antibody drug conjugates and tyrosine kinase inhibitors, are revolutionizing the therapeutic landscape of this tumor. This development coincides with the increasing knowledge of the pathogenesis and genetic alte ...[more]
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