Ontology highlight
ABSTRACT:
SUBMITTER: Te Kamp V
PROVIDER: S-EPMC7828770 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Te Kamp Verena V Friedrichs Virginia V Freuling Conrad M CM Vos Ad A Potratz Madlin M Klein Antonia A Zaeck Luca M LM Eggerbauer Elisa E Schuster Peter P Kaiser Christian C Ortmann Steffen S Kretzschmar Antje A Bobe Katharina K Knittler Michael R MR Dorhoi Anca A Finke Stefan S Müller Thomas T
Vaccines 20210114 1
The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of administration. Induction of RABV-specific binding antibodies and immunoglobulin isotypes (IgM, total IgG, IgG1, IgG2) were comparable in orally and parenterally vaccinated foxes. Differences were only observed in the induction of virus-neutrali ...[more]