Ontology highlight
ABSTRACT:
SUBMITTER: Tsogas FK
PROVIDER: S-EPMC7830067 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Tsogas Faye K FK Majerczyk Daniel D Hart Peter C PC
International journal of molecular sciences 20210116 2
Growing evidence suggests that the immune component of the tumor microenvironment (TME) may be highly involved in the progression of high-grade serous ovarian cancer (HGSOC), as an immunosuppressive TME is associated with worse patient outcomes. Due to the poor prognosis of HGSOC, new therapeutic strategies targeting the TME may provide a potential path forward for preventing disease progression to improve patient survival. One such postulated approach is the repurposing of the type 2 diabetes m ...[more]