Ontology highlight
ABSTRACT:
SUBMITTER: Crosta S
PROVIDER: S-EPMC7830149 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Crosta Simona S Boldorini Renzo R Bono Francesca F Brambilla Virginia V Dainese Emanuele E Fusco Nicola N Gianatti Andrea A L'Imperio Vincenzo V Morbini Patrizia P Pagni Fabio F
Cancers 20210114 2
Immune checkpoint inhibitors for blocking the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis are now available for squamous cell carcinoma of the head and neck (HNSCC) in relapsing and/or metastatic settings. In this work, we compared the resulting combined positive score (CPS) of PD-L1 using alternative methods adopted in routine clinical practice and determined the level of diagnostic agreement and inter-observer reliability in this setting. The study applied 5 d ...[more]