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Results of Testing Children for SARS-CoV-2 through a Community-based Testing Site.


ABSTRACT:

Objective

To describe the demographics, clinical features and test results of children referred from their primary provider for SARS-CoV-2 in the community setting.

Study design

Retrospective cross-sectional study of children ?22 years of age who were tested for SARS-CoV-2 at a community-based specimen collection site in Washington, DC affiliated with a large children's hospital between March 21 and May 16, 2020.

Results

Of the 1445 patients tested at the specimen collection site for SARS-CoV-2 virus, 408 (28.2%) had a positive PCR test. The daily positivity rate increased over the study period, from 5.4% during the first week to a peak of 47.4%. (P-trend <0.001). Patients with fever (aOR: 1.7; 95% CI 1.3, 2.3) or cough (aOR 1.4; 95% CI 1.1, 1.9) and those with known contact with someone with confirmed SARS-CoV-2 infection (aOR: 1.6; 95% CI 1.0, 2.4.) were more likely have a positive test, but these features were not-highly discriminating.

Conclusions

In this cohort of mildly symptomatic or well children and adolescents referred to a community drive-through/walk-up SARS-CoV-2 testing site because of risk of exposure or clinical illness, one in four patients had a positive test. Children and young adults represent a considerable burden of SARS-CoV-2 infection. Assessment of their role in transmission is essential to implementing appropriate control measures.

SUBMITTER: Simpson JN 

PROVIDER: S-EPMC7831849 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Publications

Results of Testing Children for Severe Acute Respiratory Syndrome Coronavirus-2 Through a Community-based Testing Site.

Simpson Joelle N JN   Goyal Monika K MK   Cohen Joanna S JS   Badolato Gia M GM   McGuire Mark M   Ralph Abigail A   Boyle Meleah D MD   Hamburger Ellen K EK   Gorman Kathleen C KC   Cora-Bramble Denice D   Delaney Meghan M  

The Journal of pediatrics 20201222


<h4>Objective</h4>To describe the demographics, clinical features, and test results of children referred from their primary provider for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in the community setting.<h4>Study design</h4>Retrospective cross-sectional study of children ≤22 years of age who were tested for SARS-CoV-2 at a community-based specimen collection site in Washington, DC, affiliated with a large children's hospital between March 21 and May 16, 2020.<h4>Results</h4>O  ...[more]

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