Ontology highlight
ABSTRACT:
SUBMITTER: Finch A
PROVIDER: S-EPMC7831916 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Finch Alina A Solomou Georgios G Wykes Victoria V Pohl Ute U Bardella Chiara C Watts Colin C
International journal of molecular sciences 20210118 2
Diffuse gliomas are the most frequent brain tumours, representing 75% of all primary malignant brain tumours in adults. Because of their locally aggressive behaviour and the fact that they cannot be cured by current therapies, they represent one of the most devastating cancers. The present review summarises recent advances in our understanding of glioma development and progression by use of various in vitro and in vivo models, as well as more complex techniques including cultures of 3D organoids ...[more]