Ontology highlight
ABSTRACT:
SUBMITTER: Lai SK
PROVIDER: S-EPMC7836766 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Lai Samuel K SK McSweeney Morgan D MD Pickles Raymond J RJ
Journal of controlled release : official journal of the Controlled Release Society 20201201
COVID-19, the disease caused by infection with SARS-CoV-2, requires urgent development of therapeutic interventions. Due to their safety, specificity, and potential for rapid advancement into the clinic, monoclonal antibodies (mAbs) represent a highly promising class of antiviral or anti-inflammatory agents. Herein, by analyzing prior efforts to advance antiviral mAbs for other acute respiratory infections (ARIs), we highlight the challenges faced by mAb-based immunotherapies for COVID-19. We pr ...[more]