Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status.
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ABSTRACT:
SUBMITTER: Rossing M
PROVIDER: S-EPMC7838175 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status.
Rossing Maria M Pedersen Christina Bligaard CB Tvedskov Tove T Vejborg Ilse I Talman Maj-Lis ML Olsen Lars Rønn LR Kroman Niels N Nielsen Finn Cilius FC Jensen Maj-Britt MB Ejlertsen Bent B
Scientific reports 20210126 1
Axillary lymph node status is an important prognostic factor for breast cancer patients and sentinel lymph node biopsy (SLNB) is a less invasive surgical proxy. We examined if consecutively derived molecular subtypes from primary breast cancers provide additional predictive value for SLNB status. 1556 patients with a breast cancer > 10 mm underwent primary surgical procedure including SLNB and tumor specimens were assigned with a transcriptomics-based molecular subtype. 1020 patients had a negat ...[more]
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