Subthreshold laser treatment for reticular pseudodrusen secondary to age-related macular degeneration.

ABSTRACT: There is a lack of treatment aimed at the regression of reticular pseudodrusen (RPD) secondary to age-related macular degeneration (AMD). The aim of this prospective, pilot study is to evaluate the safety and short-term efficacy of subthreshold laser treatment (SLT) in patients affected by RPD secondary to dry AMD (dAMD). Twenty eyes of 20 patients (mean age 78.4?±?6.8 years) with RPD secondary to dAMD were prospectively enrolled. All patients were treated in an extrafoveal area of 1.27 mm² using end-point management yellow subthreshold laser and followed for 3 months. Best-corrected visual acuity was 0.140?±?0.09 LogMAR at the baseline and no changes were observed during the follow-up (p?=?0.232). No significant worsening was disclosed before and after the treatment analyzing the macular sensitivity of the treated area (p?=?0.152). No topical and/or systemic side effects were disclosed during the 3-month follow-up. The distribution among the RPD stages changed after the treatment (p?

SUBMITTER: Querques G 

PROVIDER: S-EPMC7838261 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature