Ontology highlight
ABSTRACT:
SUBMITTER: Cheng X
PROVIDER: S-EPMC7839252 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Cheng Xianrui X Ferrell James E JE
Science (New York, N.Y.) 20191101 6465
Every daughter cell inherits two things from its mother: genetic information and a spatially organized complement of macromolecular complexes and organelles. The extent to which de novo self-organization, as opposed to inheritance of an already organized state, can suffice to yield functional cells is uncertain. We used <i>Xenopus laevis</i> egg extracts to show that homogenized interphase egg cytoplasm self-organizes over the course of ~30 minutes into compartments 300 to 400 micrometers in len ...[more]